Development of Novel Targetable Nanoparticular Systems for CRISPR/Cas9 Mediated Gene Knockout of Immune Checkpoint Protein-PD-L1 and In vitro / In vivo Evaluation of Immuno-Oncological Efficiency in Breast Cancer Model
Goal: Immuno-oncology has been involved among the most important cancer therapies after surgery, radiation therapy, and chemotherapy in the last decade. This approach is very promising because the body uses its own immune system to target cancer cells and has a long-term antitumor effect. In order for cancer immunotherapy to be successful, the recognition of cancer …