Publications

Pahal, S., Huang, F., Singh, P. et al. Enhancing vaccine stability in transdermal microneedle platforms. Drug Deliv. and Transl. Res. (2025). https://doi.org/10.1007/s13346-025-01854-4

Onan, D., Özder, M., Sipahi, M. İ., Poyraz, N., Apaydın, C., Erel‐Akbaba, G., & Akbaba, H. (2025). Microfluidics Based Particle and Droplet Generation for Gene and Drug Delivery Approaches. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 113(2). https://doi.org/10.1002/jbm.b.35530

Erel-Akbaba, G., Akbaba, H., Karaman, O., Tian, T., Tannous, B. A., & Turunc, E. (2025). Rabies virus-mimicking liposomes for targeted gene therapy in Alzheimer’s disease. International Journal of Pharmaceutics, 668, 124962. https://doi.org/10.1016/j.ijpharm.2024.124962

Akbaba, H., (2025). mRNA Aşıları. Türk Eczacılar Birliği MİSED, TR, Sayı:55-Nisan 2025 ISSN: 1303-2550

Gül, C., Gül, A., Karakavuk, T., Erkunt Alak, S., Karakavuk, M., Can, H., Değirmenci Döşkaya, A., Yavuz, İ., Kaplan, S., Erel Akbaba, G., Şen Karaman, D., Akbaba, H., Efe Köseoğlu, A., Ovayurt, T., Yüksel Gürüz, A., Ün, C., Kantarcı, A. G., & Döşkaya, M. (2024). A novel DNA vaccine encoding the SRS13 protein administered by electroporation confers protection against chronic toxoplasmosis. Vaccine, 42(24), 126065. https://doi.org/10.1016/j.vaccine.2024.06.032

Entezari, B., Akbaba, H., & Gurer-Orhan, H. (2024). Modulation of adipogenesis and lipogenesis by indomethacin and pantoprazole. Toxicology in Vitro, 100, 105895. https://doi.org/10.1016/j.tiv.2024.105895

Gül, A., Erkunt Alak, S., Can, H. et al. Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine production. Sci Rep 14, 13865 (2024). https://doi.org/10.1038/s41598-024-64690-5

Istanbullu, H., Bayraktar, G., Karakaya, G., Akbaba, H., Perk, N. E., Cavus, I., Podlipnik, C., Yereli, K., Ozbilgin, A., Debelec Butuner, B., & Alptuzun, V. (2023). Design, synthesis, in vitro – In vivo biological evaluation of novel thiazolopyrimidine compounds as antileishmanial agent with PTR1 inhibition. European Journal of Medicinal Chemistry (Vol. 247, p. 115049). Elsevier BV. https://doi.org/10.1016/j.ejmech.2022.115049

Hasan Akbaba, Gülşah Erel-Akbaba, Yücel Başpınar, and Şerif Şentürk, Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders, ACS Omega DOI: 10.1021/acsomega.3c07138

Özder, M., Erçetin, Y., & Akbaba, H. (2023). Molecular and Cellular Basics of Intermittent Fasting: Traditional Review. In Journal of Literature Pharmacy Sciences (Vol. 12, Issue 2, pp. 123–134). Turkiye Klinikleri. https://doi.org/10.5336/pharmsci.2022-94991

Mora-Buch, R., Akbaba, H., Bromley, S.K. (2023). Interactions of Tissue-Resident T Cells. In: Baldari, C.T., Dustin, M.L. (eds) The Immune Synapse. Methods in Molecular Biology, vol 2654. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3135-5_28

Akbaba, H., Baspinar, Y. (2023). Aşı Çalışmaları ve Teknolojisi- Aşıların Nanoformülasyonu. Nobel Tıp Kitabevi, TR, ISBN: 9786053358503

Debeleç-Butuner, B., Akbaba, H. (2023). Aşı Çalışmaları ve Teknolojisi– Kanser Aşıları ve İmmünoterapi. Nobel Tıp Kitabevi, TR, ISBN: 9786053358503

Kotmakci, M. Akbaba, H. (2023). Aşı Çalışmaları ve Teknolojisi- Aşı Ruhsat Dosyası ve Yasal Otorite. Nobel Tıp Kitabevi, TR, ISBN: 9786053358503

Selen İsar, Hasan Akbaba, Yiğit Şahİn, Meric A. Altinöz, Ayşe Nalbantsoy, Gülşah Erel-Akbaba & Yücel Başpınar (2022) Design and evaluation of erucic acidphytosphingosine structured cationic nanoemulsions as a plasmid DNA delivery system against breast cancer cells, Pharmaceutical Development and Technology, 27:2, 145-154, DOI: 10.1080/10837450.2021.2025247

Gulsah Erel-Akbaba, Hasan Akbaba, Erdi Keselik, Selen Akyol Bahceci, Zeynep Senyigit, Tijen Kaya Temiz, Octaarginine functionalized nanoencapsulated system: In vitro and in vivo evaluation of bFGF loaded formulation for wound healing,
Journal of Drug Delivery Science and Technology, Volume 71,2022, 103343,https://doi.org/10.1016/j.jddst.2022.103343.

Ekinci, M., Akbaba, H., Santos-Oliveira, R., & Ilem-Ozdemir, D. (2022, March 14). Development and validation of UV/VIS spectroscopy method for determination of atezolizumab in pharmaceutical products. Experimental Biomedical Research, 5(2), 175-182. https://doi.org/https://doi.org/10.30714/j-ebr.2022275813

Isar, S. , Şahin, H. Y. , Akbaba, H. , Nalbantsoy, A. , Erel Akbaba, G. & Başpınar, Y. (2022). Long-term Stability of Cationic Phytosphingosine Nanoemulsions as Delivery Systems for plasmid DNA . Celal Bayar University Journal of Science , 18 (1) , 107-118 . DOI: 10.18466/cbayarfbe.948114

Akbaba, H. , Erel-akbaba, G. & Kantarcı, A. G. (2022). Fabrication and Evaluation of Cationic Charged Magnetic Nanoparticles for Enhanced Gene Delivery . Fabad Journal of Pharmaceutical Sciences , 47 (2) , 201-212 .

Ekinci, M., dos Santos, C. C., Alencar, L. M. R., Akbaba, H., Santos-Oliveira, R., & Ilem-Ozdemir, D. (2022). Atezolizumab-Conjugated Poly(lactic acid)/Poly(vinyl alcohol) Nanoparticles as Pharmaceutical Part Candidates for Radiopharmaceuticals. ACS Omega (Vol. 7, Issue 51, pp. 47956–47966). American Chemical Society (ACS).

Erel-Akbaba, G., Akbaba, H. Investigation of the potential therapeutic effect of cationic lipoplex mediated fibroblast growth factor-2 encoding plasmid DNA delivery on wound healing. DARU J Pharm Sci 29, 329–340 (2021). https://doi.org/10.1007/s40199-021-00410-y

Akbaba H, Erel-Akbaba G, Senturk S,  Recruitment of solid lipid nanoparticles for the delivery of CRISPR/Cas9: primary evaluation of anticancer gene editing, Nanomedicine, 10.2217/nnm-2020-0412

Erel-Akbaba G, İsar S, Akbaba H. Development and Evaluation of Solid Witepsol Nanoparticles for Gene Delivery. Turk J Pharm Sci. 2021;18(3):344-351. doi:10.4274/tjps.galenos.2020.68878

Erel-Akbaba G, Akbaba H. A comparative study of cationic liposomes for gene delivery. J.Res.Pharm. 2021; 25(4): 398-406. http://dx.doi.org/10.29228/jrp.30

Akbaba, H., Özder, M. Optimization and screening of solid lipid nanoparticle production for gene delivery by factorial design and response surface methodology. Experimental Biomedical Research, 2021; 4(1): 23-37

Başpınar Y. , Akbaba H.Biosynthesis of Curcumin and Molecular Targets and the Biological Mechanism of Curcumin The Chemistry and Bioactive Components of Turmeric., Sreeraj Gopi,Sabu Thomas,Ajaikumar B Kunnumakkara,Bharat B Aggarwal,Augustine Amalraj, Editör, Royal Society of Chemistry , London, ss.196-220, 2021

Bromley SK, Akbaba H, Mani V, Mora-buch R, Chasse AY, Sama A, Luster AD,. CD49a Regulates Cutaneous Resident Memory CD8 + T Cell Persistence and Response,  CellReports, 2020;32(9):108085.

Akbaba H, Erel-Akbaba G, Kotmakçı M, Başpınar Y. Enhanced Cellular Uptake and Gene Silencing Activity of Survivin-siRNA via Ultrasound-Mediated Nanobubbles in Lung Cancer Cells. Pharm Res. 2020;37(8).  

Istanbullu H., Bayraktar G., Akbaba H., Cavus İ., Coban G., Debelec-Butuner B., Kilimcioglu A.A., Ozbilgin A., Alptuzun V., Erciyas E., Design, synthesis and in vitro biological evaluation of novel thiazolopyrimidine derivatives as antileishmanial compounds.  Archiv der Pharmazie. 2020;DOI: 10.1002/ardp.201900325

Başpinar Y, Akbaba H, Bayraktar O. Encapsulation of paclitaxel in electrosprayed chitosan nanoparticles. J. Res. Pharm. 2019;23(5):886–96

Akbaba H., Resident Memory T Cells.  Cells of the Immune System, 1st ed. InTechOpen; Croatia; 2020, http://dx.doi.org/10.5772/intechopen.90334

Baspınar Y., Erel-Akbaba G., Kotmakçı M., Akbaba H., Development and characterization of nanobubbles containing paclitaxel and survivin inhibitor YM155 against lung cancer. Int J Pharm., 2019;566:149-156

Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA., Weissleder R., Kantarcı A.G., Tannous B.,  Radiation-induced targeted nanoparticle-based gene delivery for brain tumor therapy. ACS Nano. American Chemical Society. 2019;13(4):4028–40.

Başpinar Y, Akbaba H, Bayraktar O. Encapsulation of paclitaxel in electrosprayed chitosan nanoparticles. J. Res. Pharm. 2019;23(5):886–96

Karagöz U., Kotmakçı M., Akbaba H., Çetintaş V.B., Kantarcı G., Preparation and characterization of non-viral gene delivery systems with pEGFP-C1 Plasmid DNA. Brazilian J. Pharm. Sci. 2018;54:1–11.

Akbaba H., Erel-Akbaba G., Kantarcı A.G., Development and evaluation of antisense shRNA-encoding plasmid loaded solid lipid nanoparticles against 5-α reductase activity. J. Drug Deliv. Sci. Technol. 2018;44:270–277.

Kotmakçı M., Akbaba H., Erel G., Ertan G., Kantarcı G., Improved Method for Solid Lipid Nanoparticle Preparation Based on Hot Microemulsions: Preparation, Characterization, Cytotoxicity, and Hemocompatibility Evaluation. AAPS PharmSciTech 2017;18:1355–1365

Akbaba H., Karagöz U., Selamet Y., Kantarcı A.G., Synthesis and characterization of cationic lipid coated magnetic nanoparticles using multiple emulsions as microreactors. J. Magn. Magn. Mater. 2017;426: 518–524.

Erel G., Kotmakçı M., Akbaba H., Sözer Karadağlı S., Kantarcı A.G., Nanoencapsulated chitosan nanoparticles in emulsion-based oral delivery system: In vitro and in vivo evaluation of insulin loaded formulation. J. Drug Deliv. Sci. Technol. 2016;36:161–167

Akbaba H., Demir Dora D., Kantarcı A.G., The effects of lyophilization and cryoprotectants on solid lipid nanoparticle-DNA systems. Rom. Biotechnol. Lett. 2017;22,:13186–13195

Akbaba H, Selamet Y, Kantarcı A. G., In situ production of cationic lipid coated magnetic nanoparticles in multiple emulsions for gene delivery. Marmara Pharm. J 2016; 20(2): 072-078. http://dx.doi.org/10.12991/mpj.20162069254